God shows an approach of the Islamic lifestyle in the field of applying the verses of the Quran to a happy human life. This writing is based on the great importance of Surah Al-Alak in the fundamental concepts of religion, including knowledge, dignity, monotheism, resurrection, will, choice, and justice in the meanings of its verses, and also by examining the view of Ayatollah Khamenei, which is based on the principles of a unified lifestyle. Epistemology, anthropology and ontology have stated in recent years, it deals with the semantic connection and interpretation of related words from Surah Al-Alak with their foundations in a descriptive-analytical and adaptive way. And it leads to this, that in the foundations of his epistemology, he refers to the sources of knowledge, revelation and reason, in the foundations of anthropology, to the dignity of man, will, free will, and desire for human debauchery, in the foundations of ontology, to the origin and management of existence (monotheism) and purposefulness of existence (resurrection). ) are mentioned and their connection with the words of the Surah is determined.